Harnessing nanomedicine to target NF-κB signalling in cancer: at the intersection of inflammatory signalling, metabolic reprogramming, and therapeutic innovation

Abstract The nuclear factor kappa B (NF-κB) signalling pathway is a pivotal orchestrator of inflammation, tumour progression, immune modulation, and metabolic reprogramming within the dynamic landscape of the tumour microenvironment (TME). Aberrant and sustained activation of NF-κB is frequently ass...

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Bibliographic Details

Main Authors:	Bandari BharathwajChetty, Babu Santha Aswani, Shweta S. Shinde, Mohammed S. Alqahtani, Mohamed Abbas, Gautam Sethi, Zhaowu Ma, Ajaikumar B. Kunnumakkara
Format:	Artigo
Language:	Inglês
Published:	BMC 2026-01-01
Series:	Cell Communication and Signaling
Subjects:	NF-κB pathway Nanomedicine Tumour microenvironment Immune reprogramming Therapeutic resistance Theranostics
Online Access:	https://doi.org/10.1186/s12964-025-02554-9
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