An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

Abstract Background We conducted an epigenome-wide association study (EWAS) on obesity in healthy youth and young adults and further examined to what extent identified signals influenced gene expression and were independent of cell type composition and obesity-related cardio-metabolic risk factors....

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Detalhes bibliográficos

Principais autores:	Xiaoling Wang, Yue Pan, Haidong Zhu, Guang Hao, Yisong Huang, Vernon Barnes, Huidong Shi, Harold Snieder, James Pankow, Kari North, Megan Grove, Weihua Guan, Ellen Demerath, Yanbin Dong, Shaoyong Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-01-01
coleção:	Clinical Epigenetics
Assuntos:	DNA methylation Youth African Americans Obesity Leukocytes Neutrophils
Acesso em linha:	http://link.springer.com/article/10.1186/s13148-017-0435-2
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