A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors

ABSTRACTThe World Health Organization’s goal to combat tuberculosis (TB) is hindered by the emergence of anti-microbial resistance, therefore necessitating the exploration of new drug targets. Multidrug regimens are indispensable in TB therapy as they provide synergetic bactericidal effects, shorten...

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Hlavní autoři:	Natalia Smiejkowska, Lauren Oorts, Kevin Van Calster, Linda De Vooght, Rob Geens, Henri-Philippe Mattelaer, Koen Augustyns, Sergei V. Strelkov, Dirk Lamprecht, Koen Temmerman, Yann G.-J. Sterckx, Davie Cappoen, Paul Cos
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2024-03-01
Edice:	Microbiology Spectrum
Témata:	high-throughput screening mycothione reductase tuberculosis drug discovery
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.03723-23
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