Identification of altered immune cell types and molecular mechanisms in Alzheimer’s disease progression by single-cell RNA sequencing

IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by gradual loss of cognitive function. Understanding the molecular mechanisms is crucial for developing effective therapies.MethodsData from single-cell RNA sequencing (scRNA-seq) in the GSE181279 dataset...

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Κύριοι συγγραφείς:	Hua Lin, Li Su, Daniel Mao, Grace Yang, Qi Huang, Yating Lan, Jingyi Zeng, Wenyi Song, Guining Liang, Qingyan Wei, Donghua Zou, Rongjie Li, Chanhua Zou
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2024-11-01
Σειρά:	Frontiers in Aging Neuroscience
Θέματα:	Alzheimer’s disease immune cells single-cell RNA sequencing UFC1 monocytes tlymphocytes
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fnagi.2024.1477327/full
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