Mitochondrial and energy metabolism dysfunctions are hallmarks of TDP-43G376D fibroblasts from members of an Amyotrophic Lateral Sclerosis family

Abstract Amyotrophic Lateral Sclerosis (ALS) is an incurable neurodegenerative disease, causing degeneration of motor neurons, paralysis, and death. About 5–10% of cases are associated with gene mutations inherited from a family member (fALS). Among them, mutations in the transactive-response (TAR)-...

Повний опис

Бібліографічні деталі

Автори:	Elisa Perciballi, Federica Bovio, Sara Ferro, Matilde Forcella, Jessica Rosati, Rose Mary Carletti, Angela D’Anzi, Maurizio Gelati, Vincenzo La Bella, Metello Innocenti, Rossella Spataro, Martina Pecoraro, Ivan Lombardi, Edvige Vulcano, Giorgia Ruotolo, Sara Mercurio, Mario Sabatelli, Serena Lattante, Tarja Malm, Sohvi Ohtonen, Angelo Luigi Vescovi, Paola Fusi, Daniela Ferrari
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Nature Publishing Group 2025-04-01
Серія:	Cell Death and Disease
Онлайн доступ:	https://doi.org/10.1038/s41419-025-07584-2
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!