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A new affine inhibitor of sodium pump thiacalix[4]arene С-1193 increases the intracellular concentration of Ca ions and modifies myometrium contractility

The methods of enzymatic and kinetic analysis were used to demonstrate that thiacalix[4]arene-bis-hydroxymethylphosphonic acid С-1193 had the inhibitory effect (І0.5 = 42.1 ± 0.6 nM) on Na+,K+-ATPase activity in the plasma membrane of myometrium cells with no effect on the relative activity of other...

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Autori principali: Т. О. Veklich, S. О. Cherenok, О. V. Tsymbalyuk, О. A. Shkrabak, S. O. Karakhim, A. I. Selihova, V. І. Kalchenko, S. O. Kosterin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2023-10-01
Serie:The Ukrainian Biochemical Journal
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Accesso online:http://ukrbiochemjournal.org/wp-content/uploads/2023/11/Veklich_95_5.pdf
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