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Mesangial cell-binding activity of serum immunoglobulin g in patients with lupus nephritis.

In vitro data showed that immunoglobulin G (IgG) from patients with lupus nephritis (LN) could bind to cultured human mesangial cells (HMC). The clinical relevance of such binding was unknown. Binding of IgG and subclasses was measured in 189 serial serum samples from 23 patients with Class III/IV±V...

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Autors principals: Desmond Y H Yap, Susan Yung, Qing Zhang, Colin Tang, Tak Mao Chan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2014-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4090162?pdf=render
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