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Lyophilized human platelet lysate: manufacturing, quality control, and application

BackgroundA significant number of platelet concentrates (PCs) is discarded daily in blood banks due to limited shelf life. Human platelet lysate (HPL), derived from expired PCs, has gained attention as an ethical and sustainable cell culture media supplement in biomedical research and cell therapy p...

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Huvudupphov: Kerstin Wendland, Lea Koblin, Dirk Stobbe, Anna Dahms, Debora Singer, Sander Bekeschus, Jan Wesche, Janosch Schoon, Konstanze Aurich
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2025-01-01
Serie:Frontiers in Cell and Developmental Biology
Ämnen:
human platelet lysate
freeze drying
lyophilization
mesenchymal stromal cells
sustainable cell culture
HPL
Länkar:https://www.frontiersin.org/articles/10.3389/fcell.2025.1513444/full
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