Downregulation of ANPEP Is Associated with Aggressive Prostate Cancer and Poor Disease-specific Outcomes

Background and objective: Aminopeptidase N (ANPEP) is linked to malignancy in certain tumor types, but its role in aggressive prostate cancer (PCa) is less well defined. Our aim was to characterize ANPEP expression in various PCa stages to determine whether it is a robust prognostic biomarker of agg...

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Hlavní autoři:	Ryan M. Putney, Purvish Trivedi, Shivanshu Awasthi, Amparo Serna, Jasreman Dhillon, Christopher J. Sweeney, R. Jeffrey Karnes, Matthew R. Cooperberg, Alejandro Berlin, Paul L. Nguyen, Daniel E. Spratt, Elai Davicioni, James Proudfoot, Monica Ryu, Esther Katende, Jong Y. Park, Timothy R. Rebbeck, Asmaa El-Kenawi, Kosj Yamoah
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-01-01
Edice:	European Urology Open Science
Témata:	Aminopeptidase N Prostate cancer African American men Distant metastasis Biochemical recurrence Gene set enrichment analysis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2666168325024899
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