Leptin receptor antagonist attenuates experimental autoimmune thyroiditis in mice by regulating Treg/Th17 cell differentiation

Leptin has been found to be involved in the development and progression of many autoimmune diseases. As an organ-specific autoimmune disease, the pathogenesis of Hashimoto’s thyroiditis has not been fully elucidated. It has been reported that serum leptin level is increased in Hashimoto’s thyroiditi...

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Principais autores:	Wei Wang, Bo-Tao Zhang, Qi-Lan Jiang, Han-Qing Zhao, Qin Xu, Yang Zeng, Jia-Ying Xu, Jun Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-10-01
coleção:	Frontiers in Endocrinology
Assuntos:	leptin experimental autoimmune thyroiditis (EAT) JAK2/STAT3 pathway leptin receptor antagonist NOD/ShiLtJ mouse
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1042511/full
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