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Engineered Bacillus subtilis for the de novo production of 2′-fucosyllactose

Abstract Background The most abundant human milk oligosaccharide in breast milk, 2′-fucosyllactose (2′-FL), has been approved as an additive to infant formula due to its multifarious nutraceutical and pharmaceutical functions in promoting neonate health. However, the low efficiency of de novo synthe...

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Principais autores: Quanwei Zhang, Zhenmin Liu, Hongzhi Xia, Ziyang Huang, Yonglian Zhu, Linfeng Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-06-01
Serier:Microbial Cell Factories
Fag:
Bacillus subtilis
De novo pathway
2′-fucosyllactose
GDP- L -fucose
Online adgang:https://doi.org/10.1186/s12934-022-01838-w
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