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Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens

Abstract Background Liquid-based cytology (LBC) is now a widely used method for cytologic screening and cancer diagnosis. Since the cells are fixed with alcohol-based fixatives, and the specimens are stored in a liquid condition, LBC specimens are suitable for genetic analyses. Methods Here, we esta...

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Principais autores: Toshiaki Akahane, Ikumi Kitazono, Shintaro Yanazume, Masaki Kamio, Shinichi Togami, Ippei Sakamoto, Sachio Nohara, Seiya Yokoyama, Hiroaki Kobayashi, Tsubasa Hiraki, Shinsuke Suzuki, Shinichi Ueno, Akihide Tanimoto
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-07-01
coleção:BMC Medical Genomics
Assuntos:
Endometrial cytology
LBC
NGS
Endometrial cancer
MSI
TMB
Acesso em linha:http://link.springer.com/article/10.1186/s12920-020-00753-6
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