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Design, synthesis, in silico studies and biological evaluation of 5-((E)-4-((E)-(substituted aryl/alkyl)methyl)benzylidene)thiazolidine-2,4-dione derivatives

Abstract Background Looking at the extensive biological potential of thiazolidine-2,4-dione (TZD) moiety, a new series of thiazolidine-2,4-dione analogues was synthesized. Different spectral techniques (1H-NMR, IR, MS etc.) were used to confirm the chemical structures of the synthesized analogues. T...

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Main Authors: Harsh Kumar, Aakash Deep, Rakesh Kumar Marwaha
Format: Artigo
Language:Inglês
Published: BMC 2020-03-01
Series:BMC Chemistry
Subjects:
Thiazolidin-2,4-dione
Synthesis
Antimicrobial
Antioxidant
Characterization
Online Access:http://link.springer.com/article/10.1186/s13065-020-00678-2
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