MicroRNA-181b-2 and MicroRNA-21-1 Negatively Regulate NF-κB and IRF3-Mediated Innate Immune Responses via Targeting TRIF in Teleost

Upon recognition of bacterial or viral components by Toll-like receptors (TLRs), cells could be activated to induce a series of reactions to produce inflammatory cytokines, type I interferon (IFN), and IFN stimulating genes (ISG). MicroRNAs (miRNAs) are an important regulatory molecules that are wid...

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Detalhes bibliográficos

Principais autores:	Yuena Sun, Lei Zhang, Ling Hong, Weiwei Zheng, Junxia Cui, Xuezhu Liu, Tianjun Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-12-01
coleção:	Frontiers in Immunology
Assuntos:	microRNA TRIF gene regulation immune response innate immune
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.734520/full
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