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Macrophage type 2 differentiation in a patient with laryngeal squamous cell carcinoma and metastatic prostate adenocarcinoma to the cervical lymph nodes

Abstract Background The tumor microenvironment often polarizes infiltrating macrophages towards a type 2, or M2 phenotype, that is characterized by expression of various cysteine-rich, scavenger receptors, including CD163. The primary function of M2 macrophages is to facilitate wound healing. As suc...

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Autori principali: Michael C. Topf, Madalina Tuluc, Larry A. Harshyne, Adam Luginbuhl
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017-07-01
Serie:Journal for ImmunoTherapy of Cancer
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Accesso online:http://link.springer.com/article/10.1186/s40425-017-0264-z
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