Virotherapy using myxoma virus prevents lethal graft-versus-host disease following xeno-transplantation with primary human hematopoietic stem cells.

Graft-versus-host disease (GVHD) is a potentially lethal clinical complication arising from the transfer of alloreactive T lymphocytes into immunocompromised recipients. Despite conventional methods of T cell depletion, GVHD remains a major challenge in allogeneic hematopoietic cell transplant. Here...

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Principais autores:	Eric Bartee, Amy Meacham, Elizabeth Wise, Christopher R Cogle, Grant McFadden
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2012-01-01
叢編:	PLoS ONE
在線閱讀:	http://europepmc.org/articles/PMC3419197?pdf=render
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