Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis
Abstract Background Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein recoding is the essential function o...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2017-09-01
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| Colección: | Genome Biology |
| Materias: | |
| Acceso en línea: | http://link.springer.com/article/10.1186/s13059-017-1301-4 |
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