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In silico and in vitro insights into the wound-healing potential of syringic acid: protective and regenerative effects on human fibroblasts

Abstract This study aimed to investigate the wound-healing potential of syringic acid (SA) through integrated in silico and in vitro approaches using human dermal fibroblasts (HDFs). Network pharmacology analysis identified myeloperoxidase (MPO), a key enzyme involved in oxidative stress and inflamm...

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Kaydedildi:
Asıl Yazarlar: Ufuk Okkay, İlkin Kazimov, Irmak Ferah Okkay, Azizeh Shadidizaji, Mehmet Ali Yoruk, Murat Ozdemir, Fatih Burak Yildiz, Fatma Yesilyurt, Mustafa Ozkaraca, Ahmet Hacimuftuoglu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2026-04-01
Seri Bilgileri:BMC Pharmacology and Toxicology
Konular:
Collagen synthesis
Hydroxyproline
Human dermal fibroblasts
Inflammation
Syringic acid
Wound healing
Online Erişim:https://doi.org/10.1186/s40360-026-01138-8
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