Regulation of vascular endothelial integrity by mesenchymal stem cell extracellular vesicles after hemorrhagic shock and trauma

Abstract Background Patients with hemorrhagic shock and trauma (HS/T) are vulnerable to the endotheliopathy of trauma (EOT), characterized by vascular barrier dysfunction, inflammation, and coagulopathy. Cellular therapies such as mesenchymal stem cells (MSCs) and MSC extracellular vesicles (EVs) ha...

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Hlavní autoři:	Mark Barry, Alpa Trivedi, Byron Miyazawa, Lindsay R. Vivona, David Shimmin, Praneeti Pathipati, Callie Keane, Joseph Cuschieri, Shibani Pati
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-06-01
Edice:	Journal of Translational Medicine
Témata:	Mesenchymal stem cells Mesenchymal stem cell extracellular vesicles Hemorrhagic shock Trauma
On-line přístup:	https://doi.org/10.1186/s12967-024-05406-1
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