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Fer governs mTORC1 regulating pathways and sustains viability of pancreatic ductal adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with a high percentage of morbidity. The deciphering and identification of novel targets and tools for intervening with its adverse progression are therefore of immense importance. To address this goal we adopted a specific inhi...

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Principais autores: Ilan Schrier, Orel Slotki-Itzchakov, Yoav Elkis, Nofar Most-Menachem, Orit Adato, Debora Fitoussi-Allouche, Sally Shpungin, Ron Unger, Uri Nir
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-08-01
Serier:Frontiers in Oncology
Fag:
Fer
E260
pancreatic ductal adenocarcinoma
mitochondria
AMPK
mTORC1
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2024.1427029/full
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