Curriculum Vitae of WEE2 Kinase in Homeostasis and Diseases: A Systematic Review

WEE2, an oocyte-specific kinase of the WEE family, is a core regulator of oocyte meiosis. It maintains germinal vesicle (GV) arrest and prevents premature meiotic resumption by phosphorylating cyclin-dependent kinase 1 (CDK1), thereby inhibiting maturation-promoting factor (MPF) activity. WEE2 also...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Ran Wang, Jing Yu, Yan-Jun Liu, Guo-Shu Zhao, Xiang Li, Yi-Fang Jiang, Chang-Hong Li, Guan-Jun Yang, Jiong Chen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2026-06-01
Cyfres:	Cells
Pynciau:	WEE2 cell cycle regulation WEE2 mutations reproductive diseases inhibitors
Mynediad Ar-lein:	https://www.mdpi.com/2073-4409/15/13/1147
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!