Combination of IL-17A/F and TNF-α uniquely alters the bronchial epithelial cell proteome to enhance proteins that augment neutrophil migration

Abstract Background The heterodimer interleukin (IL)-17A/F is elevated in the lungs in chronic respiratory disease such as severe asthma, along with the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α). Although IL-17A/F and TNF-α are known to functionally cooperate to exacerbate airway inf...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Anthony Altieri, Hadeesha Piyadasa, Mahadevappa Hemshekhar, Natasha Osawa, Breann Recksiedler, Victor Spicer, Pieter S Hiemstra, Andrew J Halayko, Neeloffer Mookherjee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-12-01
coleção:	Journal of Inflammation
Assuntos:	IL-17A/F TNF-α Inflammation Lung Host defence peptides Neutrophils
Acesso em linha:	https://doi.org/10.1186/s12950-022-00323-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!