Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies
Poly(ADP-ribosyl)ation (PARylation) is a dynamic protein post-translational modification (PTM) mediated by ADP-ribosyltransferases (ARTs), which regulates a plethora of essential biological processes, such as DNA repair, gene expression, and signal transduction. Among these, PAR-dependent ubiquitina...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI AG
2025-02-01
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| Serija: | Biomolecules |
| Teme: | |
| Online dostop: | https://www.mdpi.com/2218-273X/15/2/237 |
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