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Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties

Abstract Background Intravitreal injection (IVI) of antibody biologics is a key treatment approach in ophthalmology. Pharmaceutical compounding and storage of prefilled syringes for IVI must take place without impairing the structure and function of the biologics. This study investigated the effect...

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Main Authors: Øystein Kalsnes Jørstad, Stian Foss, Torleif Tollefsrud Gjølberg, Simone Mester, Mari Nyquist-Andersen, Magne Sand Sivertsen, Dag Fossum, Espen Gleditsch, Morten Carstens Moe, Jan Terje Andersen
Format: Artigo
Language:Inglês
Published: BMC 2023-11-01
Series:International Journal of Retina and Vitreous
Subjects:
Intravitreal injection
Faricimab
Compounding pharmacy
Prefilled syringes
Bi-specific binding
Online Access:https://doi.org/10.1186/s40942-023-00507-3
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