Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids

Abstract The mechanisms underlying Parkinson’s disease (PD) etiology are only partially understood despite intensive research conducted in the field. Recent evidence suggests that early neurodevelopmental defects might play a role in cellular susceptibility to neurodegeneration. To study the early d...

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Үндсэн зохиолчид:	Isabel Rosety, Alise Zagare, Claudia Saraiva, Sarah Nickels, Paul Antony, Catarina Almeida, Enrico Glaab, Rashi Halder, Sergiy Velychko, Thomas Rauen, Hans R. Schöler, Silvia Bolognin, Thomas Sauter, Javier Jarazo, Rejko Krüger, Jens C. Schwamborn
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2023-12-01
Цуврал:	npj Parkinson's Disease
Онлайн хандалт:	https://doi.org/10.1038/s41531-023-00616-8
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!