Fused extracellular vesicles from M2 macrophages and human umbilical cord mesenchymal stem cells for the targeted regulation of macrophage pyroptosis in periprosthetic osteolysis

Abstract The development of strategies for the prevention and treatment of aseptic loosening of prostheses stands as a critical area of global research interest. The pyroptosis of local macrophages triggered by wear particles plays a pivotal role in the onset of periprosthetic osteolysis and subsequ...

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Hlavní autoři:	Qimeng Liu, Tianliang Ma, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-12-01
Edice:	Journal of Extracellular Vesicles
Témata:	aseptic loosening fused extracellular vesicles macrophage pyroptosis periprosthetic osteolysis targeted therapy
On-line přístup:	https://doi.org/10.1002/jev2.70028
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