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Lower dose and weekly schedules of selinexor in multiple myeloma - updated evidence on safety and efficacy

BackgroundSelinexor, a first-in-class, oral exportin-1 inhibitor, showed activity in penta-refractory multiple myeloma (MM) in early trial exploration; however, the side-effect profile of twice-weekly dosing led to hesitant incorporation into widespread practice. Here, our objective is to provide up...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muhamed Baljevic, Gary Schiller, Tomer M. Mark, Dane R. Van Domelen, Cristina Gasparetto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2025-09-01
Saila:Frontiers in Oncology
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fonc.2025.1649493/full
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