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Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis

Abstract Ferroptosis is a regulated cell death modality that occurs upon iron-dependent lipid peroxidation. Recent research has identified many regulators that induce or inhibit ferroptosis; yet, many regulatory processes and networks remain to be elucidated. In this study, we performed a chemical g...

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Bibliografische gegevens
Hoofdauteurs: Juliane Tschuck, Lea Theilacker, Ina Rothenaigner, Stefanie A. I. Weiß, Banu Akdogan, Van Thanh Lam, Constanze Müller, Roman Graf, Stefanie Brandner, Christian Pütz, Tamara Rieder, Philippe Schmitt-Kopplin, Michelle Vincendeau, Hans Zischka, Kenji Schorpp, Kamyar Hadian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2023-10-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-023-42702-8
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