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Activating a Reserve Neural Stem Cell Population In Vitro Enables Engraftment and Multipotency after Transplantation

Summary: The olfactory epithelium (OE) regenerates after injury via two types of tissue stem cells: active globose cells (GBCs) and dormant horizontal basal cells (HBCs). HBCs are roused to activated status by OE injury when P63 levels fall. However, an in-depth understanding of activation requires...

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Bibliografische Detailangaben
Hauptverfasser: Jesse Peterson, Brian Lin, Camila M. Barrios-Camacho, Daniel B. Herrick, Eric H. Holbrook, Woochan Jang, Julie H. Coleman, James E. Schwob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-04-01
Schriftenreihe:Stem Cell Reports
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2213671119300852
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