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Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery

Abstract Background Oxylipins are potent lipid mediators demonstrated to initiate and regulate inflammation yet little is known regarding their involvement in the response to surgical trauma. As key modulators of the inflammatory response, oxylipins have the potential to provide novel insights into...

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Principais autores: Arnaud M. Wolfer, Alasdair J. Scott, Claudia Rueb, Mathieu Gaudin, Ara Darzi, Jeremy K. Nicholson, Elaine Holmes, James M. Kinross
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2017-04-01
Series:Journal of Translational Medicine
Assuntos:
Colorectal surgery
Mass spectrometry
Metabonomics
Oxylipin
Surgery
Systemic inflammatory response syndrome
Acceso en liña:http://link.springer.com/article/10.1186/s12967-017-1171-2
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