Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activityResearch in context

Summary: Background: The dicarbonyl compounds methylglyoxal (MG), glyoxal (GO) and 3-deoxyglucosone (3-DG) have been linked to various diseases. However, disease-independent phenotypic and genotypic association studies with phenome-wide and genome-wide reach, respectively, have not been provided. M...

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Detalhes bibliográficos

Principais autores:	Philip Harrer, Julica Inderhees, Chen Zhao, Barbara Schormair, Erik Tilch, Christian Gieger, Annette Peters, Olaf Jöhren, Thomas Fleming, Peter P. Nawroth, Klaus Berger, Marco Hermesdorf, Juliane Winkelmann, Markus Schwaninger, Konrad Oexle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-03-01
Colecção:	EBioMedicine
Assuntos:	Dicarbonyl compounds Phenotypic association study Genome-wide association study Kidney function Liver enzymes Glucose
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396424000422
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