Androgen promotes differentiation of PLZF+ spermatogonia pool via indirect regulatory pattern

Abstract Background Androgen plays a pivotal role in spermatogenesis, accompanying a question how androgen acts on germ cells in testis since germ cells lack of androgen receptors (AR). Promyelocytic leukemia zinc-finger (PLZF) is essential for maintenance of undifferentiated spermatogonia populatio...

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Библиографические подробности

Главные авторы:	Jingjing Wang, Jinmei Li, Wei Xu, Qin Xia, Yunzhao Gu, Weixiang Song, Xiaoyu Zhang, Yang Yang, Wei Wang, Hua Li, Kang Zou
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-05-01
Серии:	Cell Communication and Signaling
Предметы:	Androgen receptor β1-integrin PLZF Spermatogonial stem cells WT1
Online-ссылка:	http://link.springer.com/article/10.1186/s12964-019-0369-8
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