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Targeting NF-κB with Nanotherapy in a Mouse Model of Adult T-Cell Leukemia/Lymphoma

Adult T-cell leukemia/lymphoma (ATLL) is an aggressive, clonal malignancy of mature T cells caused by human T-cell leukemia virus type 1. Although it is a rare tumor type, it serves as an excellent model of a virus driven process that transforms cells and engenders a highly malignant tumor that is e...

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Principais autores: Daniel A. Rauch, John C. Harding, Lee Ratner, Samuel A. Wickline, Hua Pan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-06-01
Serier:Nanomaterials
Fag:
adult T-cell leukemia/lymphoma
human T-cell leukemia virus type 1
NF-kB activation
p5RHH
siRNA delivery
Online adgang:https://www.mdpi.com/2079-4991/11/6/1582
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