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The Hepatoprotective Effect of Piperine Against Thioacetamide-Induced Liver Fibrosis in Mice: The Involvement of miR-17 and TGF-β/Smads Pathways

Liver fibrosis is characterized by a series of events including activation of quiescent hepatic stellate cells (HSCs) into proinflammatory, contractile, and fibrogenic myofibroblasts, which is the primary trigger for the fibrogenesis process. HSC activation involves many signaling pathways such as t...

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Bibliografiske detaljer
Principais autores: Amr M. Abdelhamid, Ayman Selim, Mai A. Zaafan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-10-01
Serier:Frontiers in Molecular Biosciences
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2021.754098/full
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