Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson’s disease

Abstract Background Parkinson’s disease (PD), a chronic and severe neurodegenerative disease, is pathologically characterized by the selective loss of nigrostriatal dopaminergic neurons. Dopamine (DA), the neurotransmitter produced by dopaminergic neurons, and its metabolites can covalently modify p...

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Hlavní autoři:	Bing Chen, Qian Zhang, Xiaoru Zhong, Xinwei Zhang, Xin Liu, Hongyang Wang, Fan Yang, Jingjing Zhang, Jingnan Huang, Yin-Kwan Wong, Piao Luo, Jigang Wang, Jichao Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-01-01
Edice:	Cell Communication and Signaling
Témata:	Dopamine (DA) Parkinson’s disease (PD) Glycolysis Mitochondrial dysfunction
On-line přístup:	https://doi.org/10.1186/s12964-024-01478-0
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