Defining hypo-methylated regions of stem cell-specific promoters in human iPS cells derived from extra-embryonic amnions and lung fibroblasts.

BACKGROUND: Human induced pluripotent stem (iPS) cells are currently used as powerful resources in regenerative medicine. During very early developmental stages, DNA methylation decreases to an overall low level at the blastocyst stage, from which embryonic stem cells are derived. Therefore, pluripo...

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Bibliografiska uppgifter

Huvudupphov:	Koichiro Nishino, Masashi Toyoda, Mayu Yamazaki-Inoue, Hatsune Makino, Yoshihiro Fukawatase, Emi Chikazawa, Yoriko Takahashi, Yoshitaka Miyagawa, Hajime Okita, Nobutaka Kiyokawa, Hidenori Akutsu, Akihiro Umezawa
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Public Library of Science (PLoS) 2010-01-01
Serie:	PLoS ONE
Länkar:	http://europepmc.org/articles/PMC2946409?pdf=render
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