Pharmacodynamics of Linezolid Plus Fosfomycin Against Vancomycin–Resistant Enterococcus faecium in a Hollow Fiber Infection Model

The optimal therapy for severe infections caused by vancomycin-resistant Enterococcus faecium (VREfm) remains unclear, but the combination of linezolid and fosfomycin may be a good choice. The 24-h static-concentration time-kill study (SCTK) was used to preliminarily explore the pharmacodynamics of...

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Hlavní autoři:	Shuaishuai Wang, Huiping Liu, Jun Mao, Yu Peng, Yisong Yan, Yaowen Li, Na Zhang, Lifang Jiang, Yanyan Liu, Jiabin Li, Xiaohui Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-12-01
Edice:	Frontiers in Microbiology
Témata:	hollow-fiber infection model linezolid fosfomycin vancomycin-resistant Enterococcus faecium antibiotics resistance virulence
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.779885/full
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