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Tsukushi is essential for the development of the inner ear

Abstract Tsukushi (TSK)—a small, secreted, leucine-rich-repeat proteoglycan—interacts with and regulates essential cellular signaling cascades. However, its functions in the mouse inner ear are unknown. In this study, measurement of auditory brainstem responses, fluorescence microscopy, and scanning...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Toru Miwa, Kunimasa Ohta, Naofumi Ito, Satoko Hattori, Tsuyoshi Miyakawa, Toru Takeo, Naomi Nakagata, Wen-Jie Song, Ryosei Minoda
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-03-01
Schriftenreihe:Molecular Brain
Schlagworte:
Tsukushi
Hair cell stereocilia
Sox2
BMP4
Hearing
Online-Zugang:http://link.springer.com/article/10.1186/s13041-020-00570-z
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