Cytokine profile in childhood-onset systemic lupus erythematosus: a cross-sectional and longitudinal study

Childhood-onset systemic lupus erythematosus (cSLE) exhibits an aggressive clinical phenotype and severe complications. This could be due to a pro-inflammatory cytokine milieu. Therefore, we determined plasma levels of Th1 (IL-2, IFN-γ, TNF), Th2 (IL-4), Th17 (IL-17A, IL-6), and Treg (IL-10) cytokin...

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Principais autores:	A. Cavalcanti, R. Santos, Z. Mesquita, A.L.B.P. Duarte, N. Lucena-Silva
Format:	Artigo
Jezik:	Inglês
Izdano:	Associação Brasileira de Divulgação Científica
Serija:	Brazilian Journal of Medical and Biological Research
Teme:	Cytokines Childhood-onset systemic lupus erythematosus Disease activity SLEDAI-2K Inflammation
Online dostop:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400704&lng=en&tlng=en
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