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PACT is requisite for prostate cancer cell proliferation

Abstract PACT (encoded by the PRKRA gene) is a double-stranded RNA binding protein with defined antiviral defense and cytoplasmic RNA-induced silencing actions in mammals. We previously described a further role for PACT as a modulator of nuclear receptor (NR)-regulated gene expression. Here, we inve...

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Autori principali: Dianne J. Beveridge, Andrew J. Woo, Kirsty L. Richardson, Rikki A. M. Brown, Lisa M. Stuart, Manjot Singh, Andrew D. Redfern, Peter J. Leedman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-10-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-20494-9
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