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Low CD4/CD8 ratio is associated with increased morbidity and mortality in late and non-late presenters: results from a multicentre cohort study, 2004–2018

Abstract Background To study whether the association between the CD4/CD8 ratio variation over time and the development of clinical outcomes vary in late presenters (CD4 count < 350/µL or AIDS event at enrolment) or advanced presenters (CD4 count < 200/µL or AIDS event at enrolment). Methods We inclu...

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Hlavní autoři: Lourdes Domínguez-Domínguez, Marta Rava, Otilia Bisbal, Luis Lopez-Cortés, Joaquín Portilla, Daniel Podzamczer, Julián Olalla, Daniel Fuster, Rafael Rubio, Inmaculada Jarrín, José Antonio Iribarren, Santiago Moreno, Cohort of the Spanish HIV/AIDS Research Network (CoRIS)
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2022-04-01
Edice:BMC Infectious Diseases
Témata:
Late presentation
CD4/CD8
Clinical outcomes
AIDS events
Serious non-AIDS events
Mortality
On-line přístup:https://doi.org/10.1186/s12879-022-07352-z
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