Transcriptome-wide association study identifies genes associated with bladder cancer risk

Abstract Genome-wide association studies (GWAS) have detected several susceptibility variants for urinary bladder cancer, but how gene regulation affects disease development remains unclear. To extend GWAS findings, we conducted a transcriptome-wide association study (TWAS) using PrediXcan to predic...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Siting Li, Jiang Gui, Margaret R. Karagas, Michael N. Passarelli
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-01-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Bladder Cancer TWAS GWAS Case-control
Online-Zugang:	https://doi.org/10.1038/s41598-025-85565-3
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