Protein degradation of Lsd1 is mediated by Bre1 yet opposed by Lsd1-interacting lncRNAs during fly follicle development

Summary: Tissue development, homeostasis, and repair all require efficient progenitor expansion. Lysine-specific demethylase 1 (Lsd1) maintains plastic epigenetic states to promote progenitor proliferation while overexpressed Lsd1 protein causes oncogenic gene expression in cancer cells. However, th...

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Главные авторы:	Chun Ting Lin, Ruei-Teng Ting, Yang-Hsuan Ou, Tzu-Ling Shao, Ming-Chia Lee
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2024-05-01
Серии:	iScience
Предметы:	Biochemistry Molecular mechanism of gene regulation Developmental biology
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2589004224009052
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