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Elucidating the impact of bacterial lipases, human serum albumin, and FASII inhibition on the utilization of exogenous fatty acids by Staphylococcus aureus

ABSTRACTStaphylococcus aureus only synthesizes straight-chain saturated fatty acids (SCFAs) or branched-chain saturated fatty acids via the type II fatty acid synthesis (FASII) pathway, but as a highly adaptive pathogen, S. aureus can also utilize host-derived exogenous fatty acids (eFAs), including...

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Hoofdauteurs: Emily L. Pruitt, Rutan Zhang, Dylan H. Ross, Nathaniel K. Ashford, Xi Chen, Francis Alonzo, Matthew F. Bush, Brian J. Werth, Libin Xu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2023-12-01
Reeks:mSphere
Onderwerpen:
Staphylococcus aureus
exogenous fatty acid
bacterial lipase
human serum albumin
AFN-1252
lipidomics
Online toegang:https://journals.asm.org/doi/10.1128/msphere.00368-23
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