NormQ: RNASeq normalization based on RT-qPCR derived size factors

The merit of RNASeq data relies heavily on correct normalization. However, most methods assume that the majority of transcripts show no differential expression between conditions. This assumption may not always be correct, especially when one condition results in overexpression. We present a new met...

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Principais autores:	Ravindra Naraine, Pavel Abaffy, Monika Sidova, Silvie Tomankova, Kseniia Pocherniaieva, Ondrej Smolik, Mikael Kubista, Martin Psenicka, Radek Sindelka
格式:	Artigo
語言:	Inglês
出版:	American Association for the Advancement of Science (AAAS) 2020-01-01
叢編:	Computational and Structural Biotechnology Journal
主題:	Transcriptomics RNASeq Normalization TOMOSeq DESeq Median-of-ratios
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2001037020302737
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