Establishment and application of a method of tagged-amplicon deep sequencing for low-abundance drug resistance in HIV-1

In the latest HIV-1 global drug resistance report released by WHO, countries are advised to strengthen pre-treatment monitoring of drug resistance in AIDS patients. In this study, we established an NGS-based segmented amplification HIV-1 drug resistance mutation detection method. The pol region of H...

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Hlavní autoři:	Yang Li, Leilei Han, Yanglan Wang, Xiaolin Wang, Lei Jia, Jingyun Li, Jingwan Han, Jin Zhao, Hanping Li, Lin Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-08-01
Edice:	Frontiers in Microbiology
Témata:	HIV-1 next-generation sequencing minority drug resistance variants assessment standardization
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.895227/full
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