Mutation spectrum, expression profiling, and prognosis evaluation of Fanconi anemia signaling pathway genes for 4259 patients with myelodysplastic syndromes or acute myeloid leukemia

Abstract Background Individuals diagnosed with Fanconi anemia (FA), an uncommon disorder characterized by chromosomal instability affecting the FA signaling pathway, exhibit heightened vulnerability to the onset of myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). Methods Herein, we e...

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Principais autores:	Lixian Chang, Li Zhang, Beibei Zhao, Xuelian Cheng, Yang Wan, Ranran Zhang, Weiping Yuan, Xingjie Gao, Xiaofan Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-11-01
Series:	BMC Medical Genomics
Assuntos:	Fanconi anemia pathway AML MDS Expression Mutation
Acceso en liña:	https://doi.org/10.1186/s12920-023-01730-5
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