Acute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats

Abstract Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated. In acute toxicity tests, mice were administered total alkaloids (TA) and five in...

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Detalhes bibliográficos

Principais autores:	Yun-Li Zhao, Min Su, Jian-Hua Shang, Xia Wang, Guy Sedar Singor Njateng, Guang-Lei Bao, Jia Ma, Qing-Di Sun, Fang Yuan, Jing-Kun Wang, Xiao-Dong Luo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2020-03-01
coleção:	Natural Products and Bioprospecting
Assuntos:	Alstonia scholaris Indole alkaloids Acute toxicity Chronic toxicity Non-observed-adverse-effect-level
Acesso em linha:	https://doi.org/10.1007/s13659-020-00237-1
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