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How leaky is the gut in Parkinson’s disease?

Summary: The intestinal epithelial barrier (IEB) plays a critical role in health and disease by regulating the absorption of nutrients, electrolytes and water while preventing gut translocation of pathogens. A compromised intestinal barrier has been reported in Parkinson’s disease (PD) further reinf...

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Autori principali: Pascal Derkinderen, François Cossais, Kristína Kulcsárová, Matej Škorvánek, Loïc Sellier-Montaigne, Emmanuel Coron, Laurène Leclair-Visonneau, Silvia Cerri, Carolina Pellegrini, Malvyne Rolli-Derkinderen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2025-07-01
Serie:EBioMedicine
Soggetti:
Parkinson’s disease
Intestinal epithelial barrier
Intestinal permeability
Tight junctions
Ussing chamber
Organoids
Accesso online:http://www.sciencedirect.com/science/article/pii/S2352396425002403
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