Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses

Nanovaccines, co-delivering antigen and invariant natural killer T (iNKT) cell agonists, proved to be very effective in inducing anti-tumor T cell responses due to their exceptional helper function. However, it is known that iNKT cells are not equally present in all lymphoid organs and nanoparticles...

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Detalhes bibliográficos

Principais autores:	Yusuf Dölen, Michael Valente, Oya Tagit, Eliezer Jäger, Eric A. W. Van Dinther, N. Koen van Riessen, Martin Hruby, Uzi Gileadi, Vincenzo Cerundolo, Carl G. Figdor
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2020-01-01
coleção:	OncoImmunology
Assuntos:	cancer vaccines nanoparticle biodistribution inkt cells pd-1 4-1bb checkpoint blockade
Acesso em linha:	http://dx.doi.org/10.1080/2162402X.2020.1738813
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